Issue 5, 2007
From the journal:

Analyst

The challenge of breath analysis for clinical diagnosis and therapeutic monitoring

David Smith*a  and  Patrik Španělb  

* Corresponding authors

a Centre for Science and Technology in Medicine, School of Medicine, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, UK
E-mail: d.smith@bemp.keele.ac.uk

b J. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23, Prague 8, Czech Republic

Abstract

The potential of breath analysis for clinical diagnosis and the strengths and weaknesses of the analytical methods used are discussed. Special attention is given to selected ion flow tube mass spectrometry, SIFT-MS, using which on-line real-time analyses of single breath exhalations can be carried out. Illustrative data on the concentration distributions of several breath metabolites amongst the healthy population are presented and their relations to disease when elevated above the normal are alluded to.

Graphical abstract: The challenge of breath analysis for clinical diagnosis and therapeutic monitoring

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Article information

DOI
https://doi.org/10.1039/B700542N
Article type
Forum
Submitted
12 Jan 2007
Accepted
12 Mar 2007
First published
19 Mar 2007

Analyst, 2007,132, 390-396

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The challenge of breath analysis for clinical diagnosis and therapeutic monitoring

D. Smith and P. Španěl, Analyst, 2007, 132, 390 DOI: 10.1039/B700542N

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