Issue 7, 1997

Synthesis of 7-deaza-8-bromo cyclic adenosine 5′-diphosphate ribose: the first hydrolysis resistant antagonist at the cADPR receptor

Abstract

7-Deaza-8-bromo cyclic adenosine 5′-diphosphate ribose is synthesised from 7-deazaadenosine via 7-deaza-8-bromo nicotinamide adenine dinucleotide; it is both a more potent antagonist than the 8-bromo derivative and has the advantage of chemical and enzymatic hydrolytic stability.

Article information

Article type
Paper

Chem. Commun., 1997, 695-696

Synthesis of 7-deaza-8-bromo cyclic adenosine 5′-diphosphate ribose: the first hydrolysis resistant antagonist at the cADPR receptor

V. C. Bailey, J. K. Sethi, A. Galione and B. V. L. Potter, Chem. Commun., 1997, 695 DOI: 10.1039/A700336F

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