Issue 5, 2009
From the journal:

Analyst

Sol–gel derived nano-structured zinc oxide film for sexually transmitted disease sensor

Anees A. Ansari,*a   Renu Singh,a   G. Sumanaa  and  B. D. Malhotra*a  

* Corresponding authors

a Department of Science & Technology Centre on Biomolecular Electronics, National Physical Laboratory, Dr. K S Krishnan Marg, New Delhi 110012, India
E-mail: bansi.malhotra@gmail.com, aneesaansari@gmail.com
Fax: +91-11-45609310
Tel: +91-11-4560915

Abstract

A 20-mer thiolated oligonucleotide probe (th-ssDNA) specific to Neisseria gonorrhoeae immobilized onto a sol–gel derived nano-structured zinc oxide (ZnO) film dip-coated onto an indium-tin-oxide (ITO) glass substrate has been used for the fabrication of a DNA biosensor for sexually transmitted disease (gonorrhoea) detection using hybridization technique. The results of characterization studies carried out on this th-ssDNA–ZnO/ITO bioelectrode using X-ray diffraction, UV-Visible, Fourier-transform infrared, scanning electron microscopy and electrochemical techniques reveal the linearity as 0.000524 fmol–0.524 nmol, with a detection limit of 0.000704 fmol within 60 s.

Graphical abstract: Sol–gel derived nano-structured zinc oxide film for sexually transmitted disease sensor

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Article information

DOI
https://doi.org/10.1039/B817562D
Article type
Paper
Submitted
06 Oct 2008
Accepted
19 Feb 2009
First published
06 Mar 2009

Analyst, 2009,134, 997-1002

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Sol–gel derived nano-structured zinc oxide film for sexually transmitted disease sensor

A. A. Ansari, R. Singh, G. Sumana and B. D. Malhotra, Analyst, 2009, 134, 997 DOI: 10.1039/B817562D

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