Issue 0, 1985

Structural studies on cyanoginosins-LR, -YR, -YA, and -YM, peptide toxins from Microcystis aeruginosa

Abstract

The structures of the hepatotoxins of general name cyanoginosins-XY are proposed to be cyclo-D-Ala-L-X-erythro-β-methyl-D-isoAsp-L-Y-Adda-D-isoGlu-N-methyldehydroAla (1) where X and Y represent variable amino acids and Adda is 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid (2). The structural studies on four variant toxins utilised n.m.r. and mass spectral methods analogous to those recently used to determine the structure of cyanoginosin-LA. [graphic omitted] (1)

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1985, 2747-2748

Structural studies on cyanoginosins-LR, -YR, -YA, and -YM, peptide toxins from Microcystis aeruginosa

D. P. Botes, P. L. Wessels, H. Kruger, M. T. C. Runnegar, S. Santikarn, R. J. Smith, J. C. J. Barna and D. H. Williams, J. Chem. Soc., Perkin Trans. 1, 1985, 2747 DOI: 10.1039/P19850002747

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