Issue 0, 1980
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Tritiated peptides. Part 8. Synthesis of [3,5-3H2-Tyr2]-, [4-3H-Phe7]-, and [3,5-3H2-Tyr23]-human corticotrophin

Derek E. Brundish  and  Roy Wade  

Abstract

Syntheses are described of human corticotrophin nonatriacontapeptides separately labelled with tritium in the tyrosine residues at positions 2 and 23 and in the phenylalanine residue at position 7 at specific radioactivities of 49, 25, and 31 Ci mmol–1 respectively. Labelling was by reductive deiodination of protected precursors. Evidence for the integrity of the final products is provided by amino-acid analysis, column chromatography, and bioassay, supported by chemical and enzymic analytical data.

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Article information

DOI
https://doi.org/10.1039/P19800000462
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1980, 462-465

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Tritiated peptides. Part 8. Synthesis of [3,5-3H2-Tyr2]-, [4-3H-Phe7]-, and [3,5-3H2-Tyr23]-human corticotrophin

D. E. Brundish and R. Wade, J. Chem. Soc., Perkin Trans. 1, 1980, 462 DOI: 10.1039/P19800000462

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