Electrochemical trifluoroalkylation/annulation for the synthesis of CF3-functionalized tetrahydroquinolines and dihydroquinolinones†
Cheng-He
Zhou 
a
and
Zhong-Lin
Zang
*a
a
and
Zhong-Lin
Zang
*a
Abstract
Tuning the electronic structure of protecting groups on the nitrogen atom of substrates has emerged as an effective strategy to achieve the tandem trifluoromethylation/C(sp2)–H annulation using Langlois’ reagent as the CF3 source for the electrochemical synthesis of functionalized tetrahydroquinolines and dihydroquinolinones.
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