Issue 40, 2022
From the journal:

Organic & Biomolecular Chemistry

Visible-light-induced alkylation of 2-iminochromene†

Shashank Singh ORCID logo a  and  Ravi P. Singh ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, India
E-mail: ravips@chemistry.iitd.ac.in

Abstract

A metal-free, photochemical protocol for C-4 alkylation of 2-iminochromene has been developed by employing the naturally abundant feedstock carboxylic acid. Selective C-4 alkylation under photoredox conditions to access C-4 alkylated 2-iminochromene in up to 81% yield was achieved. In addition, biologically relevant chromophores can be easily incorporated under this protocol.

Graphical abstract: Visible-light-induced alkylation of 2-iminochromene

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D2OB01584F
Article type
Communication
Submitted
31 Aug 2022
Accepted
15 Sep 2022
First published
16 Sep 2022

Org. Biomol. Chem., 2022,20, 7891-7895

Permissions

Request permissions

Visible-light-induced alkylation of 2-iminochromene

S. Singh and R. P. Singh, Org. Biomol. Chem., 2022, 20, 7891 DOI: 10.1039/D2OB01584F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements