Controlled synthesis of double-shelled CeO2 hollow spheres and enzyme-free electrochemical bio-sensing properties for uric acid

Lijun Han; Rongji Liu; Chunshan Li; Honghua Li; Cuixia Li; Guangjin Zhang; Jiannian Yao

doi:10.1039/C2JM32804F

Controlled synthesis of double-shelled CeO₂ hollow spheres and enzyme-free electrochemical bio-sensing properties for uric acid†

Lijun Han,^a Rongji Liu,^ac Chunshan Li,^a Honghua Li,^a Cuixia Li,^ac Guangjin Zhang*^a and Jiannian Yao^b

* Corresponding authors

^a Beijing Key Laboratory of Ionic Liquids Clean Process, State Key Laboratory of Multiphase Complex System, Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, P.R. China
E-mail: zhanggj@home.ipe.ac.cn
Fax: +86 10-62528935
Tel: +86 10-62528935

^b Beijing National Laboratory for Molecular Science, Key Laboratory of Photochemistry, Institute of Chemistry, Chinese Academy of Science, Beijing, China

^c Graduate University of Chinese Academy of Sciences, 100190 Beijing, China

Abstract

A simple solvothermal method has been used to synthesize novel double-shelled CeO₂ hollow spheres (HSs) in a mixed solvent of PEG-400 and H₂O. The structure and morphology of the CeO₂ HSs were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and nitrogen adsorption–desorption isotherms. The SEM and TEM images indicated that the as-prepared double-shelled CeO₂ (about 400–500 nm in diameter) were aggregates of nanoparticles with sizes of about 15 nm. The shape and composition of the as-obtained products could be controlled by adjusting the ratio of PEG-400 and H₂O in the solvothermal process. The effects of PEG-400/H₂O ratio, solvothermal temperature and reaction time on the morphology evolution of as-prepared products were investigated, and the possible formation mechanism was proposed based on nucleation and the Ostwald ripening process as well as the soft-template function of PEG-400. In addition, the double-shelled CeO₂ HSs show high electrocatalytic activity towards uric acid (UA) oxidation and thus exhibit good biosensor activities toward the detection of trace amounts of UA.

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Article information

DOI: https://doi.org/10.1039/C2JM32804F
Article type: Paper
Submitted: 04 May 2012
Accepted: 30 Jun 2012
First published: 03 Jul 2012

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J. Mater. Chem., 2012,22, 17079-17085

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Controlled synthesis of double-shelled CeO₂ hollow spheres and enzyme-free electrochemical bio-sensing properties for uric acid

L. Han, R. Liu, C. Li, H. Li, C. Li, G. Zhang and J. Yao, J. Mater. Chem., 2012, 22, 17079 DOI: 10.1039/C2JM32804F

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Journal of Materials Chemistry