Issue 11, 2005
From the journal:

Lab on a Chip

Microfluidic capturing-dynamics of paramagnetic bead suspensions

Christian Mikkelsena  and  Henrik Bruus*a  

* Corresponding authors

a MIC—Department of Micro and Nanotechnology, Technical University of Denmark, DTU-Bldg. 345 east, DK-2800 Kongens Lyngby, Denmark
E-mail: bruus@mic.dtu.dk

Abstract

We study theoretically the capturing of paramagnetic beads by a magnetic field gradient in a microfluidic channel treating the beads as a continuum. Bead motion is affected by both fluidic and magnetic forces. The transfer of momentum from beads to the fluid creates an effective bead–bead interaction that greatly aids capturing. We demonstrate that for a given inlet flow speed a critical density of beads exists above which complete capturing takes place.

Graphical abstract: Microfluidic capturing-dynamics of paramagnetic bead suspensions

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Article information

DOI
https://doi.org/10.1039/B507104F
Article type
Paper
Submitted
19 May 2005
Accepted
08 Sep 2005
First published
27 Sep 2005

Lab Chip, 2005,5, 1293-1297

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Microfluidic capturing-dynamics of paramagnetic bead suspensions

C. Mikkelsen and H. Bruus, Lab Chip, 2005, 5, 1293 DOI: 10.1039/B507104F

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