Issue 26, 2020, Issue in Progress
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RSC Advances

The construction of fluorophoric thiazolo-[2,3-b]quinazolinone derivatives: a multicomponent domino synthetic approach†

Prajna Parimita Mohanta,a   Hari Narayan Patia  and  Ajaya Kumar Behera ORCID logo *a  

* Corresponding authors

a School of Chemistry, Sambalpur University, Jyoti Vihar, Burla-768019, India
E-mail: ajaykumar.behera@yahoo.com, ajaykumar.behera@suniv.ac.in

Abstract

Acid-mediated one-pot domino reactions of substituted 2-amino thiazoles, substituted benzaldehydes and cyclic diketones have been developed for the synthesis of novel and architecturally unique thiazolo[2,3-b]quinazolinone derivatives under microwave irradiation. In this protocol, a series of thiazolo[2,3-b]quinazolinone derivatives have been synthesized and the excellent fluorescence behaviors of some of the molecules have been reported based on the incorporation of different electron-donating and electron-withdrawing substituents on the aryl moieties of the target molecules.

Graphical abstract: The construction of fluorophoric thiazolo-[2,3-b]quinazolinone derivatives: a multicomponent domino synthetic approach

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Article information

DOI
https://doi.org/10.1039/D0RA01066A
Article type
Paper
Submitted
04 Feb 2020
Accepted
28 Mar 2020
First published
17 Apr 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 15354-15359

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The construction of fluorophoric thiazolo-[2,3-b]quinazolinone derivatives: a multicomponent domino synthetic approach

P. P. Mohanta, H. N. Pati and A. K. Behera, RSC Adv., 2020, 10, 15354 DOI: 10.1039/D0RA01066A

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