Cross coupling of benzylammonium salts with boronic acids using a well-defined N-heterocyclic carbene–palladium(ii) precatalyst†
Tao
Wang, 
*ab
Lantao
Liu
*ab
*ab
Lantao
Liu
*ab
Abstract
N-heterocyclic carbene–palladium(II)-catalyzed cross-coupling of benzylammonium salts with arylboronic acids for the synthesis of diarylmethane derivatives via C–N bond activation has been developed. Notably, in the presence of the easily prepared and bench-stable Pd-PEPPSI precatalyst, the Csp3–N bond activation of the benzylammonium salt even proceeded smoothly in isopropanol at room temperature.
- This article is part of the themed collection: Editors’ collection: Catalytic Organic Transformations
Please wait while we load your content...
