Issue 59, 2018
From the journal:

Chemical Communications

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines†

Weiguang Yang,a   Dayun Huang,a   Xiaobao Zeng,a   Dongping Luo,a   Xinyan Wang*a  and  Yuefei Hu ORCID logo *a  

* Corresponding authors

a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
E-mail: wangxinyan@mail.tsinghua.edu.cn, yfh@mail.tsinghua.edu.cn

Abstract

A highly reactive intermediate N-sulfonyl acetylketenimine was generated from a 3-butyn-2-one participating CuAAC/ring-opening method. Its high reactivity due to bearing two EWGs allowed us to offer the first example of a reaction between ketenimine and amide to synthesize N-sulfonyl amidines efficiently.

Graphical abstract: N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C8CC04699A
Article type
Communication
Submitted
12 Jun 2018
Accepted
03 Jul 2018
First published
03 Jul 2018

Chem. Commun., 2018,54, 8222-8225

Permissions

Request permissions

N-Sulfonyl acetylketenimine as a highly reactive intermediate for the synthesis of N-sulfonyl amidines

W. Yang, D. Huang, X. Zeng, D. Luo, X. Wang and Y. Hu, Chem. Commun., 2018, 54, 8222 DOI: 10.1039/C8CC04699A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements