Direct halogenative dearomatization of 2-naphthols by NXS (X = Cl, Br) in water†
Abstract
A direct halogenative dearomatization of substituted 2-naphthols was achieved by NXS (X = Cl, Br) in environmentally friendly water at room temperature. The reaction exhibited broad substrate scope, convenient operation and high yields (up to 99%), thus providing a facile route to dearomatic products and complex polycyclic frameworks.