Issue 10, 2007

The Baylis–Hillman reaction: a novel source of attraction, opportunities, and challenges in synthetic chemistry

Abstract

The Baylis–Hillman reaction is a successful, useful, and atom-economical carbon–carbon bond forming reaction, which has grown from an obscure level to the level of high synthetic popularity due to its operational simplicity and also due to the enormous applications of the Baylis–Hillman adducts in organic synthesis. In this tutorial review, we briefly describe the way this reaction has grown to its present heights and the opportunities, attractions, and challenges the reaction offers with respect to its asymmetric and intramolecular versions, and mechanistic aspects.

Graphical abstract: The Baylis–Hillman reaction: a novel source of attraction, opportunities, and challenges in synthetic chemistry

Article information

Article type
Tutorial Review
Submitted
30 Oct 2006
First published
23 Mar 2007

Chem. Soc. Rev., 2007,36, 1581-1588

The Baylis–Hillman reaction: a novel source of attraction, opportunities, and challenges in synthetic chemistry

D. Basavaiah, K. Venkateswara Rao and R. Jannapu Reddy, Chem. Soc. Rev., 2007, 36, 1581 DOI: 10.1039/B613741P

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