Issue 7, 1990

Determination of 1,4-dioxane in cosmetic products by high-performance liquid chromatography

Abstract

A rapid high-performance liquid chromatographic procedure has been developed for the assay of 1,4-dioxane in cosmetic products. After solid-phase extraction, using Bond Elut CN and Bond Elut C18 cartridges, samples were analysed directly on a LiChrospher CH-8 reversed-phase column with spectrophotometric detection at 200 nm and acetonitrile-water as eluent. Recovery of 1,4-dioxane from different cosmetic matrices was between 81.5 and 90.1% in the 30–90 µg g–1 range. The minimum quantifiable amount was 6.5 µg g–1. The method is simple, reproducible and specific and is suitable for routine analyses of commercial cosmetics.

Article information

Article type
Paper

Analyst, 1990,115, 929-931

Determination of 1,4-dioxane in cosmetic products by high-performance liquid chromatography

S. Scalia, M. Guarneri and E. Menegatti, Analyst, 1990, 115, 929 DOI: 10.1039/AN9901500929

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