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Association of Glutathione-S-Transferase-P1 (GSTP1) Polymorphism 105 Ile>Val with Chronic Lung Disease in Preterm Infants

Journal of Perinatology volume 24, page 800 (2004)Cite this article

Dear Editor:

We read the paper by Manar et al.1 with interest. They showed a decreased frequency of the GSTP1 105 Val/Val genotype in infants with chronic lung disease (CLD) compared with term control infants. We have also been investigating the association of various gene polymorphisms in neonatal disorders, including the 105 Ile>Val polymorphism in exon 5 of the GSTP1 gene.

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References

  1. Manar MH, Brown MR, Gauthier TW, Brown LS . Association of glutathione-S-transferase-P1 polymorphisms with bronchopulmonary dysplasia. J Perinatol 2004;24:30–35.

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  2. Rodriguez-Frias F, Gonzalez C, Costa X, et al. Screening for polymorphisms in exon 5 of the glutathione-S-transferase P1 gene. Thorax 2000;55:535–536.

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Authors and Affiliations

  1. Department of Child Health, Regional NICU, University of Liverpool, Liverpool Women's Hospital, Merseyside, Liverpool, UK

    Richard W I Cooke MD, Josephine A Drury MPhIL, Michael W Beresford MD, PhD & Nigel J Shaw MD

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  1. Richard W I Cooke MD
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  2. Josephine A Drury MPhIL
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  3. Michael W Beresford MD, PhD
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  4. Nigel J Shaw MD
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Cooke, R., Drury, J., Beresford, M. et al. Association of Glutathione-S-Transferase-P1 (GSTP1) Polymorphism 105 Ile>Val with Chronic Lung Disease in Preterm Infants. J Perinatol 24, 800 (2004). https://doi.org/10.1038/sj.jp.7211145

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