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Nephrocalcinosis in Premature Infants

Variability in Ultrasound Detection

Abstract

OBJECTIVE:

To measure variability among radiologists in the ultrasound diagnosis of nephrocalcinosis in premature infants.

METHODOLOGY:

In this prospective multicenter study, renal ultrasounds were performed on 54 very low birth weight infants using a 5.0- and 7.5-MHz transducer, and these ultrasounds were read independently by three radiologists. κ coefficients were calculated to assess variability in identification of nephrocalcinosis among the radiologists.

RESULTS:

The κ coefficient (± confidence intervals) using a 5.0-MHz transducer was 0.143 (0.108, 0.178); using the 7.5-MHz transducer, the κ coefficient was 0.268 (0.243, 0.293). All three radiologists agreed in their identification of nephrocalcinosis on 3 of 54 ultrasounds using a 5.0-MHz transducer; a total of 6 of 54 ultrasounds obtained using a 7.5-MHz transducer were read as positive by all three radiologists.

CONCLUSION: There is significant variability among radiologists in the ultrasound identification of nephrocalcinosis in premature infants; a 7.5-MHz ultrasound transducer is associated with less variability in recognizing this lesion.

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This work was supported by Ross Products Division of AbbottLaboratories.

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Campfield, T., Bednarek, F., Pappagallo, M. et al. Nephrocalcinosis in Premature Infants. J Perinatol 19, 498–500 (1999). https://doi.org/10.1038/sj.jp.7200263

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  • DOI: https://doi.org/10.1038/sj.jp.7200263

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