Lysosomal hyperacidification is regarded as a hallmark of autophagy. A new pH nanosensor that detects shifts in near-infrared emission bands is used to quantify cellular and intratumoral lysosomal pH.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Lawrence, R. E. & Zoncu, R. Nat. Cell Biol. 21, 133–142 (2019).
Mulcahy Levy, J. M. & Thorburn, A. Cell Death Differ. 27, 843–857 (2020).
Mijin, K. et al. Nat. Chem. Biol. https://doi.org/10.1038/s41589-023-01364-9 (2023).
Hou, J. T. et al. Chem. Soc. Rev. 46, 2076–2090 (2017).
Steinegger, A., Wolfbeis, O. S. & Borisov, S. M. Chem. Rev. 120, 12357–12489 (2020).
Welsher, K., Sherlock, S. P. & Dai, H. Proc. Natl Acad. Sci. USA 108, 8943–8948 (2011).
Kwon, H. et al. J. Phys. Chem. C 119, 3733–3739 (2015).
Chen, Q. et al. Nat. Commun. 11, 6290 (2020).
Fang, H. et al. Nat. Commun. 12, 109 (2021).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Qiu, K., Tian, Z. & Diao, J. Monitoring lysosomal acidity. Nat Chem Biol 19, 1434–1435 (2023). https://doi.org/10.1038/s41589-023-01348-9
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41589-023-01348-9
