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TRANSPLANTATION

Cell therapy can enable minimization of immunosuppression

Nature Reviews Nephrology volume 16, pages 486–487 (2020)Cite this article

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Long-term immunosuppression in transplant recipients is associated with important adverse effects including increased risk of infection and malignancy. New data from the ONE Study suggests that use of cell-based medicinal products containing regulatory immune cells is a potentially useful therapeutic strategy to enable minimization of immunosuppression in these patients.

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Authors and Affiliations

  1. Department of Surgery, Division of Organ Transplantation, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    James M. Mathew & Joseph R. Leventhal

  2. Department of Microbiology–Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    James M. Mathew

Authors
  1. James M. Mathew
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  2. Joseph R. Leventhal
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Corresponding authors

Correspondence to James M. Mathew or Joseph R. Leventhal.

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The authors declare no competing interests.

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Cite this article

Mathew, J.M., Leventhal, J.R. Cell therapy can enable minimization of immunosuppression. Nat Rev Nephrol 16, 486–487 (2020). https://doi.org/10.1038/s41581-020-0330-5

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