Timely and comprehensive updating of treatment guidelines remains a challenge and necessity in medical oncology. Herein we discuss our assessment of how trial results with four off-patent drugs have been considered for integration into major guidelines in the absence of a commercial sponsor, in which we found reasons for concern.
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The authors thank P. Pantziarka (Anticancer Fund) for discussions and assistance in preparing this article.
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Related links
ASCO Guidelines Evidence Submission Form: https://www.surveymonkey.com/r/guidelineevidence
ASCO Guidelines Methodology Manual: https://www.asco.org/sites/new-www.asco.org/files/content-files/advocacy-and-policy/documents/2022-Guidelines-Methodology-Manual-with-links.pdf
ESMO eUpdate standard operating procedures: https://www.esmo.org/content/download/121792/2307979/1/ESMO-eUpdate-SOP.pdf
NCCN Submission Request History: https://www.nccn.org/guidelines/submissions-request-to-the-guidelines-panels/submission-request-history
Transparency of the NCCN Guidelines Development Process: https://www.nccn.org/guidelines/guidelines-process/transparency-process-and-recommendations
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Bouche, G., Meheus, L. Ensuring completeness and timeliness of cancer treatment guidelines. Nat Rev Clin Oncol 19, 563–564 (2022). https://doi.org/10.1038/s41571-022-00646-w
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DOI: https://doi.org/10.1038/s41571-022-00646-w
