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Stroke

'Time is brain' after stroke, regardless of age and severity

Nature Reviews Neurology volume 10, pages 675–676 (2014)Cite this article

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Two recent studies highlight the importance of prompt, coordinated intervention after stroke. A meta-analysis confirms that intravenous thrombolysis is effective within 4.5 h of onset, irrespective of age (below or above 80 years) and stroke severity. Another study demonstrates successful reorganization of care through centralization of stroke services in England.

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Acknowledgements

H.J A. has received funding for the TEMPiS network from the Bavarian health insurance companies, the Bavarian Ministry of Labour and Social Affairs, the German Foundation for Stroke Aid and the German Federal Ministry of Education and Research (BMBF), as well as funding for the STEMO project from the 'Zukunftsfonds Berlin', and funding for the INSPiRE-TMS trial by the Federal Ministry of Education and Research (BMBF) via the grant Center for Stroke Research Berlin (01 EO 0801). J.S. has received funding for the Mismatch24 study from the BMBF via the grant Center for Stroke Research Berlin (01 EO 0801), as well as funding for the Stroke Unit Plus Study via a grant from the Corona Foundation.

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Authors and Affiliations

  1. Klinik für Neurologie & Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, 12200, Germany

    Heinrich J. Audebert

  2. Klinik für Neurologie & Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany

    Jan Sobesky

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Correspondence to Heinrich J. Audebert.

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Competing interests

H.J.A. has received consultancy honoraria from Lundbeck Pharma, Pfizer and Bayer Vital, as well as speaker's honoraria from Takeda Pharma, Boehringer Ingelheim, Lundbeck, Bayer Vital, UCB, Pfizer, Bristol-Myers Squibb and Sanofi-Synthélabo. J.S. has received consultancy and speaker's honoraria from Boehringer Ingelheim, Bayer Vital, BMS, Maquet, Pfizer, Paion, Sanofi-Synthélabo, Takeda Pharma and UCB.

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Audebert, H., Sobesky, J. 'Time is brain' after stroke, regardless of age and severity. Nat Rev Neurol 10, 675–676 (2014). https://doi.org/10.1038/nrneurol.2014.194

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