Uncertainty exists over the time frame and biological development of cerebral aneurysms. In a new study, Etminan et al. used carbon birth dating to assess turnover of collagen in ruptured and unruptured aneurysms. In all samples, the collagen was on average <5 years old. As carbon levels correlated with patient age and aneurysm size, the authors suggest that this method could be useful for modelling of aneurysm development.
ORIGINAL RESEARCH PAPER
Etminan, N. et al. Exploring the age of intracranial aneurysms using carbon birth dating. Stroke doi:10.1161/STROKEAHA.112.673806
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Carbon birth dating—a new method to investigate development of cerebral aneurysms?. Nat Rev Neurol 9, 121 (2013). https://doi.org/10.1038/nrneurol.2013.18
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DOI: https://doi.org/10.1038/nrneurol.2013.18