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Polycystic kidney disease

Progression of polycystic kidney disease—a lack of progress?

Despite an explosion in understanding of the disease process, the rates of patients with autosomal dominant polycystic kidney disease starting renal replacement therapy show no signs of slowing. Indeed, rates among people aged ≥70 years have increased, reflecting a greater propensity to offer renal replacement therapy to this age group.

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Acknowledgements

The ANZDATA Registry is funded by the Australian Organ and Tissue Donation and Transplantation Authority, the New Zealand Ministry of Health and Kidney Health Australia.

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Correspondence to Stephen McDonald.

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S.M. and G.R. are site-investigators in an ongoing clinical trial of tolvaptan for ADPKD (Otsuka Pharmaceutical Ltd)

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McDonald, S., Rangan, G. Progression of polycystic kidney disease—a lack of progress?. Nat Rev Nephrol 10, 489–491 (2014). https://doi.org/10.1038/nrneph.2014.138

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