Plasma exchange (PLEX) is often included in the initial therapy of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis who present with severe kidney failure. However, new long-term follow-up data from the MEPEX trial suggest that PLEX may not improve survival in these patients.
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Bomback, A., Appel, G. ANCA-associated GN—to PLEX or not to PLEX?. Nat Rev Nephrol 9, 436–438 (2013). https://doi.org/10.1038/nrneph.2013.126
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DOI: https://doi.org/10.1038/nrneph.2013.126
