Lactobacillus acidophilus may have a role in the treatment of chronic fatigue syndrome, particularly when incorporated into 'floating' alginate beads. In a rat model of chronic fatigue syndrome induced by physical fatigue (swimming), L. acidophilus (free or delivered in beads) had a significant and beneficial effect on immobility and postswim fatigue time; levels of oxidonitrosative stress and tumor necrosis factor were also attenuated and spleen and thymus size restored.
ORIGINAL RESEARCH PAPER
Singh, P. K. et al. Role of Lactobacillus acidophilus loaded floating beads in chronic fatigue syndrome: behavioral and biochemical evidences. Neurogastroenterol. Motil. doi:10.1111/j.1365-2982.2011.01861.x
Rights and permissions
About this article
Cite this article
Lactobacillus acidophilus can attenuate the symptoms of chronic fatigue syndrome. Nat Rev Gastroenterol Hepatol 9, 186 (2012). https://doi.org/10.1038/nrgastro.2012.26
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2012.26