Abstract
The economic effects of the possible introduction of 'follow-on' protein products have been the subject of recent debate. Here, we aim to explore the economic issues surrounding this debate using three measures: total sales, product complexity and patent expiry. Our analysis shows that the sales of therapeutic protein products are concentrated in a relatively small number of branded products, which may be the most attractive targets for follow-on development. For the years 2013–2015, we estimate that products representing US$20 billion in annual sales — approximately half of all sales in 2006 — can be expected to lose patent protection.
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Lanthier, M., Behrman, R. & Nardinelli, C. Economic issues with follow-on protein products. Nat Rev Drug Discov 7, 733–737 (2008). https://doi.org/10.1038/nrd2636
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DOI: https://doi.org/10.1038/nrd2636
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