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Timing isn't everything

Nature Neuroscience volume 13, pages 277–279 (2010)Cite this article

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Synaptic long-term potentiation and depression are determined by the frequency and timing of coactivated synapses. A new model explains many experimental plasticity observations and allows new predictions about neural circuit function.

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Figure 1: Membrane potential–based rules for LTP and LTD.

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Authors and Affiliations

  1. Department of Neurobiology & Physiology at Northwestern University, Evanston, Illinois, USA

    Nelson Spruston & Jianhua Cang

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  1. Nelson Spruston
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  2. Jianhua Cang
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Correspondence to Nelson Spruston.

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The authors declare no competing financial interests.

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Spruston, N., Cang, J. Timing isn't everything. Nat Neurosci 13, 277–279 (2010). https://doi.org/10.1038/nn0310-277

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