Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

An old acquaintance resurfaces in human mesothelioma

Nature Medicine volume 3, pages 839–840 (1997)Cite this article

The large T antigen of SV40 virus may promote the development of mesotheliomas by interacting with and inactivating tumor suppressor proteins (pages 908–916).

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Ludlow, J.W. Interactions between SV40 largetumor antigen and the growth suppressor proteins pRB and p53. FASEB J. 7, 866–871 (1993).

    Article  CAS  Google Scholar 

  2. Vousden, K. Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes. FASEB J. 7, 872–879 (1993).

    Article  CAS  Google Scholar 

  3. zur Hausen, H. Viruses in human cancers. Science 254, 1167–1173 (1991)

    Article  CAS  Google Scholar 

  4. Carbone, M. et al. Simian virus 40-like sequences in human pleural mesothelioma. Oncogene 9, 1781–1790 (1994)

    CAS  Google Scholar 

  5. Carbone, M. et al. SV40-like sequences in human bone tumors. Oncogene 13, 527–535 (1996)

    CAS  PubMed  Google Scholar 

  6. Martini, F. et al. SV40 early region and large T antigen in human brain tumors, peripheral blood cells, and sperm fluids from healthy individuals. Cancer Res. 56, 4820–4825 (1996).

    CAS  PubMed  Google Scholar 

  7. De Luca, A. et al. The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large-T antigen in human mesotheliomas. Nature Med. 3, 913–916 (1997)

    Article  CAS  Google Scholar 

  8. Carbone, M. et al. Simian virus-40 large-T antigen binds p53 in human mesotheliomas. Nature Med. 3, 908–912 (1997).

    Article  CAS  Google Scholar 

  9. Qian, W. et al. Role of p53 mutation in polyoma virus-induced tumorigenesis. J. Gen. Virol. 78, 893–903 (1997).

    Article  Google Scholar 

  10. Heintz, N.H., Janssen, Y.M. & Mossman, B.T. Persistent induction of c-fos and c-jun expression by asbestos. Proc. Natl. Acad. Sci. USA 90, 3299–3303 (1993).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Microbiology and Tumor Biology Center, Karolinska Institute, Box 280, S-171 77, Stockholm, Sweden

    Klas G. Wiman & George Klein

Authors
  1. Klas G. Wiman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. George Klein
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wiman, K., Klein, G. An old acquaintance resurfaces in human mesothelioma. Nat Med 3, 839–840 (1997). https://doi.org/10.1038/nm0897-839

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nm0897-839

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing