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RNA interference meets HIV-1: Will silence be golden?

RNA interference first gained notoriety in invertebrates and plants as a means to target genes for deactivation. Now, in vitro studies suggest that in human cells, this process can inhibit HIV-1 replication and potentially act as a novel and potent anti-retroviral therapy (pages 683–688).

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Figure 1: A model for RNA interferrence (RNAi) in a cell.

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Pomerantz, R. RNA interference meets HIV-1: Will silence be golden?. Nat Med 8, 659–660 (2002). https://doi.org/10.1038/nm0702-659

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