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Lighting up TCR takes advantage of serial triggering

Nature Immunology volume 3, pages 895–896 (2002)Cite this article

The complex interaction with APCs that is required for T cell activation is not well understood. A combination of experimental data and mathematical modeling provides insight into the competition between serial triggering and kinetic proofreading.

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Figure 1: “Lighting up” of TCRs for internalization.

K. R.

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Authors and Affiliations

  1. Department of Chemical Engineering and Department of Chemistry, University of California and Physical Biosciences Division and Materials Science Division, Lawrence Berkeley National Laboratory, Berkeley, 94720, CA, USA

    Arup K. Chakraborty

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  1. Arup K. Chakraborty
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Chakraborty, A. Lighting up TCR takes advantage of serial triggering. Nat Immunol 3, 895–896 (2002). https://doi.org/10.1038/ni1002-895

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