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MyD88 beyond Toll

The adaptor protein MyD88 is involved in interleukin 1 receptor and Toll-like receptor signaling. Unexpectedly, new evidence shows that MyD88 also participates in interferon-γ-induced cellular responses.

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Figure 1: Model of MyD88-mediated TLR and IFN-γ signaling.

Katie Ris

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Han, J. MyD88 beyond Toll. Nat Immunol 7, 370–371 (2006). https://doi.org/10.1038/ni0406-370

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