Abstract
Angiotensin II has an uncertain molecular basis in aqueous solution; two models are proposed here, a β-turn and a γ-turn model, of which the latter seems the more likely.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
We are sorry, but there is no personal subscription option available for your country.
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Page, I. H., and McCubbin, J. W., Renal Hypertension, 80 (Year Book Medical Publ. Inc., 1968).
Printz, M. P., and Galardy, R. E., Fed. Proc., 30, 1200 (1971).
Printz, M. P., Williams, H. P., and Craig, L. C., Pharmacologist, 13, 234 (1971).
Printz, M. P., Williams, H. P., and Craig, L. C., Proc. US Nat. Acad. Sci. (in the press).
Smeby, R. R., Arakawa, K., Bumpus, F. M., and Marsh, M. M., Biochim. Biophys. Acta, 58, 550 (1962).
Brant, D. A., Macromolecules, 1, 291 (1968).
Geddes, A. J., Parker, K. D., Atkins, E. D. T., and Beighton, E., J. Mol. Biol., 32, 343 (1968).
Stern, A., Gibbons, W. A., and Craig, L. C., Proc. US Nat. Acad. Sci., 61, 734 (1968).
Deber, C. M., Bovey, F. A., Carver, J. P., and Blout, E. R., J. Amer. Chem. Soc., 92, 6191 (1970).
Tonelli, A. E., J. Amer. Chem. Soc., 92, 6187 (1970).
Fermandjian, S., Morgat, J. L., Fromageot, P., Lutz, C., and Leichnam, J. P. (in the press).
Urry, D. W., and Ohnishi, M., Spectroscopic Approaches to Biomolecular Conformation (edit. by Urry, D. W.), 263 (American Medical Association, Chicago, 1970).
Bumpus, F. M., Khairallah, P. A., Arakawa, K., Page, I. H., and Smeby, R. R., Biochim. Biophys. Acta, 46, 38 (1971).
Printz, M. P., and von Hippel, P. H., Proc. US Nat. Acad. Sci., 53, 363 (1965).
Marshall, G. R., Vine, W., and Needleman, P., Proc. US Nat. Acad. Sci., 67, 1624 (1970).
Craig, L. C., Harfenist, E. J., and Paladini, A. C., Biochemistry, 3, 764 (1964).
Franze de Fernandez, M. T., Delius, A. E., and Paladini, A. C., Biochim. Biophys. Acta, 154, 223 (1968).
Roberts, G. C. K., and Jardetsky, O., Adv. Protein Chem., 25, 447 (1970).
Scheraga, H. A., Adv. Phys. Org. Chem., 6, 103 (1968).
Winkler, F. K., and Dunitz, J. D., J. Mol. Biol., 59, 169 (1971).
Ramachandran, G. N., and Sasisekharan, V., Adv. Protein Chem., 23, 283 (1968).
Gibson, K. D., and Scheraga, H. A., Biopolymers, 4, 709 (1966).
Go, M., Go, N., and Scheraga, H. A., J. Chem. Phys., 54, 4489 (1971).
Nemethy, G., Ann. New York Acad. Sci., 155, 492 (1969).
Kurcbart, H., Coir, A., Vancheri, L., and Rosa, U., Biochim. Biophys. Acta, 230, 160 (1971).
Hageman, W. E., Hofmann, K., Ertel, R. J., and Buckley, J. P., J. Pharmacol. Exper. Ther., 168, 295 (1969).
Hofmann, K., Andreatta, R., Buckley, J. P., Hageman, W. E., and Shapiro, A. P., J. Amer. Chem. Soc., 90, 1654 (1968).
IUPAC-IUB Commission on Biochemical Nomenclature, J. Mol. Biol., 52, 1 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PRINTZ, M., NÉMETHY, G. & BLEICH, H. Proposed Models for Angiotensin II in Aqueous Solution and Conclusions about Receptor Topography. Nature New Biology 237, 135–140 (1972). https://doi.org/10.1038/newbio237135a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/newbio237135a0
This article is cited by
-
Conformational analysis of cyclic angiotensin II analogues
Letters in Peptide Science (1996)
-
Proton NMR studies of angiotensin II and its analogs in aqueous solution
Journal of Protein Chemistry (1991)
-
Selective potentiating effects of metal ions on vasopressom
Experientia (1974)
-
NMR Evidence against γ Turn and β Turn Models of Angiotensin II in Aqueous Solution
Nature New Biology (1973)
