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Stuck without Traffic Jam

During organogenesis different cells must recognize and adhere to each other in a complicated orchestration of cell movements that requires intricate regulation of cell adhesions. A Maf transcription factor, Traffic jam, has been found to regulate a panel of cell adhesion molecules, and the interactions between germ cells and somatic cells to shape the mature gonad.

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Figure 1: Somatic cells migrate to surround germline cells in the ovary.
Figure 2: Differential adhesion can drive tissue structure.

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McNeill, H. Stuck without Traffic Jam. Nat Cell Biol 5, 948–949 (2003). https://doi.org/10.1038/ncb1103-948

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