The combined use of laser ablation and live imaging in Drosophila melanogaster embryos provides new ways to visualize the dynamics of wound healing. Analysis of lesions made in living embryos mutant for small GTPases reveal distinct and unexpected roles for actin cables and protrusions in wound repair. Hole closure is definitely more complex than simply pulling a string.
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Noselli, S. Drosophila, actin and videotape — new insights in wound healing. Nat Cell Biol 4, E251–E253 (2002). https://doi.org/10.1038/ncb1102-e251b
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DOI: https://doi.org/10.1038/ncb1102-e251b
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