Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

An actin fishnet for DNA

It has long been thought that gathering chromosomes during spindle assembly is exclusively the responsibility of microtubules. However, a recent study by Lénárt et al. shows that, in larger cells, a collapsing network of actin filaments ensnares and transports the chromosomes, bringing them in range for microtubule capture.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Schematic diagram illustrating congression in oocytes.

References

  1. Lénárt, P. & Ellenberg, J. Curr. Opin. Cell Biol. 15, 88–95 (2003).

    Article  Google Scholar 

  2. Gadde, S. & Heald, R. Curr. Biol. 14, R797–R805 (2004).

    Article  CAS  Google Scholar 

  3. Lénárt, P. et al. Nature 10.1038/nature03810 (in the press).

  4. Rogers, S. L. & Gelfand, V. I. Curr. Biol. 8, 161–164 (1998).

    Article  CAS  Google Scholar 

  5. Gard, D. L., Cha, B. J. & Roeder, A. D. Zygote 3, 17–26 (1993).

    Article  Google Scholar 

  6. Leader, B. et al. Nature Cell Biol. 4, 921–928 (2002).

    Article  CAS  Google Scholar 

  7. Ankenbauer, T. et al. Nature 342, 822–825 (1989).

    Article  CAS  Google Scholar 

  8. Holaska, J. M., Kowalski, A. K. & Wilson, K. L. PLoS Biol. 2, 1354–1362 (2004).

    Article  CAS  Google Scholar 

  9. Clark, T. G. & Rosenbaum, J. L. Cell 18, 1101–1108 (1979).

    Article  CAS  Google Scholar 

  10. Fujisaki, H., Albanesi, J. P. & Korn, E. D. J. Biol. Chem. 260, 11183–11189 (1985).

    CAS  PubMed  Google Scholar 

  11. Hellewell, S. B. & Taylor, D. L. J. Cell Biol. 83, 633–648 (1979).

    Article  CAS  Google Scholar 

  12. von Dassow, G. & Schubiger, G. J. Cell Biol. 127, 1637–1653 (1994).

    Article  CAS  Google Scholar 

  13. Murthy, K. & Wadsworth, P. Curr. Biol. 15, 724–731 (2005).

    Article  CAS  Google Scholar 

  14. Guha, M., Zhou, M. & Wang Y. L. Curr. Biol. 15, 732–736 (2005).

    Article  CAS  Google Scholar 

  15. Simerly, C., Nowak, G., de Lanerolle, P. & Schatten, G. Mol. Biol. Cell 9, 2509–2525 (1998).

    Article  CAS  Google Scholar 

  16. Weber, K. L. et al. Nature 431, 325–329 (2004).

    Article  CAS  Google Scholar 

  17. Rodriguez, O. C. et al. Nature Cell Biol. 5, 599–609 (2003).

    Article  CAS  Google Scholar 

  18. Wollman, R. et al. Curr. Biol. 15, 828–832 (2005).

    Article  CAS  Google Scholar 

  19. Carazo-Salas, R. E. & Karsenti, E. Curr. Biol. 13, 1728–1733 (2003).

    Article  CAS  Google Scholar 

  20. Rosenblatt, J., Cramer, L. P., Baum, B. & McGee, K. M. Cell 117, 361–372 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Miller, A., Bement, W. An actin fishnet for DNA. Nat Cell Biol 7, 775–776 (2005). https://doi.org/10.1038/ncb0805-775

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncb0805-775

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing