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Apparent treatment-resistant hypertension among elderly Korean hypertensives: an insight from the HIT registry

Journal of Human Hypertension volume 28, pages 201–205 (2014)Cite this article

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Abstract

The aim of this study was to determine the clinical characteristics of patients with resistant hypertension (RH) and predictors among elderly Korean hypertensives. This prospective, multi-center, observational study evaluated 2439 elderly hypertensive patients between December 2008 and November 2011, who visited secondary hypertension clinics for high blood pressure (BP). Patients were categorized as resistant if their BP was ⩾140/90 mm Hg and if they reported using antihypertensive medications from three different drug classes, including a diuretic or drugs from ⩾4 antihypertensive drug classes, regardless of BP. Characteristics of patients with RH were compared with those of patients who were controlled with one or two antihypertensive medications after 6-month antihypertensive treatment. In comparison with 837 patients with non-RH, 404 patients with RH were more likely to be aware of their status of high BP before enrollment and have a high baseline systolic BP ⩾160 mm Hg, microalbuminuria, high body mass index (BMI) ⩾24 kg m−2 and diabetes mellitus (DM). In drug-naive patients, awareness of hypertension at baseline was the only independent predictor for RH. In elderly Korean hypertensives, BMI (⩾24 kg m−2), baseline systolic BP (⩾160 mm Hg), microalbuminuria, DM and awareness of hypertension showed an association with RH.

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Acknowledgements

The HIT study was supported by Sanofi, Korea by providing web pages/server and collecting patients’ data.

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Authors and Affiliations

  1. Division of Cardiology, Dongtan Sacred Heart Hospital, Hallym University, Hwaseong, Korea

    S-W Choi, M-K Kim & K-H Ryu

  2. Department of Internal Medicine, Hangang Sacred Heart Hospital, Hallym University, Seoul, Korea

    S W Han

  3. Division of Cardiology, Gachon University Gil Hospital, Incheon, Korea

    S H Han

  4. Division of Cardiology, Gangnam Severance Hospital, Yonsei University, Seoul, Korea

    B K Lee

  5. Department of Internal Medicine, Gwangju Christian Hospital, Gwangju, Korea

    S U Lee

  6. Division of Cardiology, Daejeon St. Mary's Hospital, The Catholic University of Korea, Daejeon, Korea

    S-H Hur

  7. Division of Cardiology, Bundang Cha Hospital, Cha University, Seongnam, Korea

    S W Lim

  8. Division of Cardiology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea

    K W Moon

  9. Division of Cardiology, Ulsan University Hospital, Ulsan, Korea

    S G Lee

  10. Department of Internal Medicine, Dongkang Medical Center, Ulsan, Korea

    S H Lee

  11. Division of Cardiology, Wonkwang University School of Medicine and Hospital, Iksan, Korea

    S K Oh

  12. Division of Cardiology, Chonbuk National University Hospital, Jeonju, Korea

    J G Chea

  13. Division of Cardiology, Jeju National University Hospital, Jeju, Korea

    S J Joo

  14. Division of Cardiology, Chungbuk National University Hospital, Cheongju, Korea

    M C Jo

  15. Division of Cardiology, Chooncheon Sacred Heart Hospital, Hallym University, Chooncheon, Korea

    K-S Hong

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  1. S-W Choi
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  3. S W Han
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  4. S H Han
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  7. S-H Hur
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  8. S W Lim
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  9. K W Moon
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  10. S G Lee
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  11. S H Lee
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  12. S K Oh
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  13. J G Chea
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  14. S J Joo
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  15. M C Jo
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  16. K-S Hong
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  17. K-H Ryu
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Consortia

on behalf of the investigators of the Korean Registry on the Antihypertensive Treatment Patterns in the Elderly: the Hypertension In elderly patienTs (HIT) study

Corresponding author

Correspondence to K-H Ryu.

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The authors declare no conflict of interest.

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Choi, SW., Kim, MK., Han, S. et al. Apparent treatment-resistant hypertension among elderly Korean hypertensives: an insight from the HIT registry. J Hum Hypertens 28, 201–205 (2014). https://doi.org/10.1038/jhh.2013.76

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  • DOI: https://doi.org/10.1038/jhh.2013.76

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