Abstract
In order to simulate the outcome of the P-M status of Eurasian populations of Drosophila melanogaster, the evolution of experimental mixed-strains was monitored for up to 50 generations. The results were compared with the evolution in natura of European populations sampled in 1981–83 and 1986–87 over a similar period of time. Different combinations of P and M′ strains, Q and M′ strains, M′ and M′ strains and M and M′ strains were set up at 25° C and duplicated at 13° C night–21° C day. The possibility of a change towards a P type only appeared with the introduction of the strong P strain Harwich into Eurasian strains. Strains with strength similar to that of Harwich are not currently found in wild populations. With the introduction of weak P and Q strains of the strength presently observed in western Europe, experimental populations evolved slowly towards a Q state or a weak M′ state. M′–M′ mixed populations resulted in strong M′ strains, as was the case for M–M′ populations. In these cases. P sequences were not eliminated. In wild populations both genetic and molecular analyses showed no significant differences, over a five year period, for GD sterility potentials, for total P copy number or for distribution of the full-sized and KP elements. Changes in Eurasian populations are probably taking place at a very low rate and may even have stopped, leading to a quasi-stable differentiation over the continent. During the different steps of progressive invasion of P transposable elements, several deleted elements developed and natural selection may have acted on them. The possibility of the selection of different types of regulatory mechanisms according to the presence of different kinds of derivative elements, leading to a world-wide differentiation between P–Q and M′ strains is discussed.
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Anxolabéhère, D, and Periquet, G. 1987. P-homologous sequences in Diptera are not restricted to the Drosophilidae family. Genet Iber, 39, 211–222.
Anxolabéhère, D, Nouaud, D, and Periquet, G. 1982. Etude de la variabilité du système P-M de dysgénésie des hybrides entre populations de Drosophila melanogaster. CR Acad Sci Paris, 294, 913–918.
Anxolabéhère, D, Kai, H, Nouaud, D, Periquet, G, and Ronsseray, S. 1984. The geographical distribution of P-M hybrid dysgenesis in Drosophila melanogaster. Genet Sel Evol, 16, 15–26.
Anxolabéhère, D, Nouaud, D, Periquet, G, and Tchen, P. 1985. P-element distribution in Eurasian populations of Drosophila melanogaster: a genetic and molecular analysis. Proc Natl Acad Sci USA, 85, 5418–5422.
Anxolabéhère, D, Nouaud, D, Periquet, G, and Ronsseray, S. 1986. Evolution des potentialités dysgénésiques du système P-M dans des populations expérimentales mixtes P, Q, M et M′ de Drosophila melanogaster. Genetica, 69, 81–95.
Anxolabéhère, D, Benes, H, Nouaud, D, and Periquet, G. 1987. Evolutionary steps and transposable elements in Drosophila melanogaster: the missing RP type obtained by genetic transformation. Evolution, 41, 846–853.
Anxolabéhère, D, Kidwell, M G, and Periquet, G. 1988a. Molecular characteristics of diverse populations are consistent with a recent invasion of Drosophila melanogaster by mobile P elements. Mol Biol Evol, 5, 252–269.
Anxolabéhère, D, Charles-Palabost, L, Fleuriet, S, and Periquet, G. 1988b. Temporal surveys of French populations of Drosophila melanogaster: P–M system, enzymatic polymorphism and infection by the sigma virus. Heredity, 61, 121–131.
Bingham, P M, Kidwell, M G, and Rubin, G M. 1982. The molecular basis of P-M hybrid dysgenesis: the role of the P element, a P strain specific transposon family. Cell, 29, 995–1004.
Black, D M, Jackson, M S, Kidwell, M G, and Dover, G A. 1987. KP elements repress P-induced hybrid dys-genesis in D. melanogaster. EMBO Journal, 6, 4113–4123.
Boussy, I A, Healy, M J, Oakeshott, J G, and Kidwell, M G. 1988. Molecular Analysis of the P–M Gonadal Dysgenesis Cline in Eastern Australian Drosophila melanogaster. Genetics, 119, 889–902.
Daniels, S B, and Strasbaugh, L D. 1986. The distribution of P-element sequences in Drosophila: the willistoni and saltans species groups. J Mol Evolution, 32, 138–148.
Daniels, S B, Clark, S H, Kidwell, M G, and Chovnick, A. 1987. Genetic transformation of Drosophila melanogaster with an autonomous P element: phenotypic and molecular analyses of long-established transformed lines. Genetics, 115, 711–723.
David, J R, and Capy, P. 1988. Genetic variation of Drosophila melanogaster natural populations. Trends Genet, 4, 106–111.
Engels, W R. 1979. Hybrid dysgenesis in Drosophila melanogaster: rules of inheritance of female sterility. Genet Res, Camb, 33, 219–236.
Engels, W R. 1989. P-elements in Drosophila. In: Mobile DNA. D. Berg and M. Howe Eds., American Society of Microbiology (In press).
Engels, W R, and Preston, C R. 1980. Components of hybrid dysgenesis in a wild population of Drosophila melanogaster. Genetics, 95, 111–128.
Fitzpatrick, B, and Sved, J A. 1986. High levels of fitness modifiers induced by hybrid dysgenesis in Drosophila melanogaster. Genet Res, Camb, 48, 89–94.
Izaabel, H, Ronsseray, S, and Anxolabéhère, D. 1987. Temporal stability of P-M polymorphism in a natural population of Drosophila melanogaster. Genet Res, Camb, 50, 99–103.
Jackson, M S, Black, D M, and Dover, G A. 1988. Amplification of KP elements associated with the repression of hybrid dysgenesis in Drosophila melanogaster. Genetics, 120, 1003–1013.
Kidwell, M G. 1979. Hybrid dysgenesis in Drosophila melanogaster: the relationships between the P-M and I-R interaction systems. Genet Res Camb, 33, 205–217.
Kidwell, M. 1983. Evolution of hybrid dysgenesis determinants in Drosophila melanogaster. Proc Natl Acad Sci USA, 80, 1655–1659.
Kidwell, M G, Kidwell, J F, and Sved, J A. 1977. Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics, 86, 813–833.
Kidwell, M G, Novy, J B, and Feeley, S M. 1981. Rapid unidirectional change of hybrid dysgenesis potential in Drosophila. J Hered, 72, 32–38.
Kidwell, M G, and Novy, J B. 1985. The hybrid dysgenesis determinants in North American populations of D. melanogaster. Drosophila Inform Serv, 61, 97–100.
Kidwell, M G, Kimura, K, and Black, D M. 1988. Evolution of Drosophila melanogaster genomes following P element contamination. Genetics, 119, 815–828.
Kiyasu, P K, and Kidwell, M G. 1984. Hybrid dysgenesis in Drosophila melanogaster: The evolution of mixed P and M populations maintained at high temperature. Genet Res Camb, 44, 251–259.
Mackay, T F. 1986. Transposable element-induced fitness mutations in Drosophila melanogaster. Genet Res Camb, 48, 77–87.
Maniatis, T, Fritsch, E, and Sambrook, J. 1982. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York, pp. 545.
Ohare, K, and Rubin, G M. 1983. Structures of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome. Cell, 34, 25–35.
Periquet, G, Hamelin, M H, Bigot, Y, and Lepissier, A. 1989a. Geographical and historical patterns of distribution of hobo elements in Drosophila melanogaster populations. J Evol Biol, 2, 223–239.
Periquet, G, Hamelin, M H, Bigot, Y, and Kai, H. 1989b. Presence of the deleted hobo element Th in Eurasian populations of Drosophila melanogaster. Genet Sel Evol, 21, 107–111.
Ronsseray, S, Lehman, M, and Periquet, G. 1989. Comparison of the regulation of P elements in M and M′ strains of Drosophila melanogaster. Genet Res Camb (In press).
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Periquet, G., Ronsseray, S. & Hamelin, M. Are Drosophila melanogaster populations under a stable geographical differentiation due to the presence of P elements?. Heredity 63, 47–58 (1989). https://doi.org/10.1038/hdy.1989.74
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DOI: https://doi.org/10.1038/hdy.1989.74
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