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The next frontier for malaria vaccination

Hot on the heels of the first approved vaccine for malaria, researchers are racing to develop even better shots that tackle the parasite at every stage of its life cycle.
  1. Cassandra Willyard

    1. Cassandra Willyard is a science journalist in Madison, Wisconsin.

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In 1967, Austrian–Brazilian immunologist Ruth Nussenzweig made a momentous discovery. By blasting malaria parasites with radiation, she could weaken them. When injected into mice, these feeble parasites were unable to replicate and cause disease. But they could prompt an immune response.

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Nature 618, S20-S22 (2023)

doi: https://doi.org/10.1038/d41586-023-02048-z

This article is part of Nature Outlook: Malaria, an editorially independent supplement produced with the financial support of third parties. About this content.

Updates & Corrections

  • Correction 06 July 2023: This Outlook article erroneously stated that RTS,S is administered to children from the age of 6 weeks. In fact, children must be at least 5 months old.

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