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  • RESEARCH HIGHLIGHT

Huge trial yields disappointing results on colonoscopy benefits

Analysis suggests that the screening method cuts risk of colorectal cancer by only a modest amount.
Three-dimensional fluorescence micrograph of human colon cancer cells in green and purple colours

Human colon-cancer cells. A randomized trial failed to show that the screening technique called colonoscopy strongly reduces deaths from colorectal cancer. Credit: Dr Torsten Wittmann/Science Photo Library

Colonoscopies might reduce the risk of colorectal cancer less than expected, according to a landmark trial1.

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Nature 610, 423 (2022)

doi: https://doi.org/10.1038/d41586-022-03228-z

References

  1. Bretthauer, M. et al. N. Engl. J. Med. www.nejm.org/doi/full/10.1056/NEJMoa2208375 (2022).

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