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Patterns of Base Modification in tRNA

Abstract

WE have previously demonstrated that the N-hydroxy-succinimide ester of phenoxyacetic acid (HSP) reacts with certain species of rat liver tRNA1. The reactive species were identified by an alteration in their elution pattern on benzoylated DEAE-cellulose chromatography. Those species that reacted with HSP were not eluted from the column unless ethanol was included in the eluting solvent.

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FRIEDMAN, S. Patterns of Base Modification in tRNA. Nature New Biology 244, 18–20 (1973). https://doi.org/10.1038/newbio244018a0

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