Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Getting a bead on receptor movements

Studies of populations of receptor proteins suggest that their number and location are highly regulated. Single-particle tracking of glycine receptors now reveals the direct movement of receptors between different clusters of the anchoring protein gephyrin.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Experimental design for single-particle tracking of neurotransmitter receptors.

References

  1. Akaaboune, M., Culican, S. M., Turney, S. G. & Lichtman, J. W. Science 286, 503–507 (1999).

    Article  CAS  Google Scholar 

  2. Craig, A. M. Neuron 21, 459–462 (1998).

    Article  CAS  Google Scholar 

  3. Turrigiano, G. G. Neuron 26, 5–8 (2000).

    Article  CAS  Google Scholar 

  4. Meier, J., Vannier, C., Serge, A., Triller, A. & Choquet, D. Nat. Neurosci. 4, 253–260 (2001).

    Article  CAS  Google Scholar 

  5. Sanes, J. R. & Lichtman, J. W. Annu. Rev. Neurosci. 22, 389–442 (1999).

    Article  CAS  Google Scholar 

  6. Kneussel, M. & Betz, H. Trends Neurosci. 23, 429–435 (2000).

    Article  CAS  Google Scholar 

  7. Saxton, M. J. & Jacobson, K. Annu. Rev. Biophys. Biomol. Struct. 26, 373–399 (1997).

    Article  CAS  Google Scholar 

  8. Meyer, G., Kirsch, J., Betz, H. & Langosch, D. Neuron 15, 563–572 (1995).

    Article  CAS  Google Scholar 

  9. Levi, S., Vannier, C. & Triller, A. J. Cell Sci. 111, 335–345 (1998).

    CAS  Google Scholar 

  10. Kirsch, J. & Betz, H. Nature 392, 717–720 (1998).

    Article  CAS  Google Scholar 

  11. Ehlers, M. D. Neuron 28, 511–525 (2000).

    Article  CAS  Google Scholar 

  12. Lee, H. K., Barbarosie, M., Kameyama, K., Bear, M. F. & Huganir, R. L. Nature 405, 955–959 (2000).

    Article  CAS  Google Scholar 

  13. Sarma, V. R., Silverton, E. W., Davies, D. R. & Terry, W. D. J. Biol. Chem. 246, 3753–3759 (1971).

    CAS  PubMed  Google Scholar 

  14. Noji, H., Yasuda, R., Yoshida, M. & Kinosita, K. Jr. Nature 386, 299–302 (1997).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marie Craig, A., Lichtman, J. Getting a bead on receptor movements. Nat Neurosci 4, 219–220 (2001). https://doi.org/10.1038/85042

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/85042

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing