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Structural biology

Ion pump in the movies

Nature volume 432, pages 286–287 (2004)Cite this article

Insight into how membrane ion pumps work requires structural snapshots of various stages of their catalytic cycle. Now a fifth freeze-frame image of a calcium pump in action adds to a striking body of work on this protein.

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Figure 1: The Post–Albers cycle: states of the ion pump Ca2+-ATPase as it transports Ca2+ ions into the sarcoplasmic reticulum.
Figure 2: Ca2+-ATPase in the five key states for which high-resolution structures are available.

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  1. Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Marie-Curie-Strasse 15, Frankfurt am Main, D-60439, Germany

    C. Roy D. Lancaster

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  1. C. Roy D. Lancaster
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Lancaster, C. Ion pump in the movies. Nature 432, 286–287 (2004). https://doi.org/10.1038/432286a

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