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Oligonucleotide-based therapeutics

Oligonucleotide analogues offer several mechanisms for potential therapeutic action; triple helix agents that inhibit disease-causing genes at the DNA level show particular promise.

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Riordan, M., Martin, J. Oligonucleotide-based therapeutics. Nature 350, 442–443 (1991). https://doi.org/10.1038/350442a0

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