Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Auxin induces rapid changes in phosphatidylinositol metabolites

Nature volume 331, pages 176–178 (1988)Cite this article

Abstract

The plant growth-hormone auxin (indole-3-acetic acid, IAA) is involved in regulating such diverse processes as cell elongation, cell division and differentiation. The sequence of events leading to the various phenomena is still poorly understood. Both changes in extra- and intracellular pH (refs 1–4) and selective transcription5,6 are known to be induced by auxin. Evidence for auxin receptors at the plasmalemma membrane has been reported7, but the signal transduction pathway is not known, for this nor for other plant hormones. In animal cells, hydrolysis of inositolphos-pholipids is a major mechanism for transmembrane signalling in response to external stimuli such as hormones, growth factors, neurotransmitters, antigens or light (reviewed in refs 8–11). Here we report that auxin can generate transient changes in inositol-1,4,5-trisphosphate (Ins(l,4,5)P3) and inositol bisphosphate (InsP2) within minutes in Catharanthus roseus cells arrested in G1 . These changes are accompanied by a redistribution within the polyphosphoinositide fraction. As the physiological response to auxin addition is to relieve the arrest in G1, we suggest that these effects are an element in the signal transduction of this plant hormone.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hager, A., Menzel, H. & Krauss, A. Planta 100, 47–75 (1971).

    Article  CAS  Google Scholar 

  2. Cleland, R. E. A. Rev. Pl. Physiol. 22, 197–222 (1971).

    Article  CAS  Google Scholar 

  3. Felle, H., Brummer, B., Bertl, A. & Parish, R. W. Proc. natn. Acad. Sci. U.S.A. 83, 8992–8995 (1986).

    Article  ADS  CAS  Google Scholar 

  4. Taiz, L. A. Rev. Pl. Physiol. 35, 585–657 (1984).

    Article  CAS  Google Scholar 

  5. Hagen, G., Kleinschmidt, A. & Guilfoyle, T. Planta 162, 147–153 (1984).

    Article  CAS  Google Scholar 

  6. Theologis, A., Huynh, T. V. & Davies, R. W. J. molec. Biol. 183, 53–68 (1985).

    Article  CAS  Google Scholar 

  7. Löbler, M. & Klämbt, D. J. biol. Chem. 260, 9854–9859 (1985).

    PubMed  Google Scholar 

  8. Berridge, M. J. Biol. Chem. Hoppe-Seyler 367, 447–456 (1986).

    Article  CAS  Google Scholar 

  9. Nishizuka, Y. Nature 308, 693–698 (1984).

    Article  ADS  CAS  Google Scholar 

  10. Michell, B. Nature 319, 176–177 (1986).

    Article  ADS  CAS  Google Scholar 

  11. Majerus, P. W. et al. Science 234, 1519–1526 (1986).

    Article  ADS  CAS  Google Scholar 

  12. Ettlinger, C., Schindler, J. & Lehle, L. Planta 168, 101–105 (1986).

    Article  CAS  Google Scholar 

  13. Murashige, T. & Skoog, F. Physiologia Pl. 15, 437–497 (1962).

    Article  Google Scholar 

  14. Clarke, N. G. & Dawson, R. M. C. Biochem. J. 195, 301–306 (1981).

    Article  CAS  Google Scholar 

  15. Irvine, R. F., Änggord, E. E., Letcher, A. J. & Downes, C. P. Biochem. J. 229, 505–511 (1985).

    Article  CAS  Google Scholar 

  16. Turk, J., Wolf, B. A. & McDaniel, M. L. Biochem. J. 237, 259–263 (1986).

    Article  CAS  Google Scholar 

  17. Hawkins, P. T., Stephens, L. & Downes, C. P. Biochem. J. 238, 507–516 (1986).

    Article  CAS  Google Scholar 

  18. Berridge, M. J., Downes, C. P. & Hanley, M. R. Biochem. J. 206, 587–595 (1982).

    Article  CAS  Google Scholar 

  19. Burgess, G. M., McKinney, J. S., Irvine, R. F. & Putney, J. W. Jr Biochem. J. 232, 237–243 (1985).

    Article  CAS  Google Scholar 

  20. Bansal, V. S., Inhorn, R. C. & Majerus, P. W. J. biol. Chem. 262, 9444–9447 (1987).

    CAS  PubMed  Google Scholar 

  21. Ackermann, K. E., Gish, B. G., Honchar, M. P. & Sherman, W. R. Biochem. J. 242, 517–524 (1987).

    Article  CAS  Google Scholar 

  22. Irvine, R. F., Letcher, A. J., Heslop, J. P. & Berridge, M. J. Nature 320, 631–634 (1986).

    Article  ADS  CAS  Google Scholar 

  23. Streb, H., Irvine, R. F., Berridge, M. J. & Schulz, I. Nature 306, 67–69 (1983).

    Article  ADS  CAS  Google Scholar 

  24. Berridge, M. J. & Irvine, R. F. Nature 312, 315–321 (1984).

    Article  ADS  CAS  Google Scholar 

  25. Hepler, P. K. & Wayne, R. O. A. Rev. Pl. Physiol. 36, 397–439 (1985).

    Article  CAS  Google Scholar 

  26. Drobak, B. K. & Ferguson, I. B. Biochem. biophys. Res. Commun. 130, 1241–1246 (1985).

    Article  CAS  Google Scholar 

  27. Rincon, M. & Boss, W. F. Pl. Physiol. 83, 395–398 (1987).

    Article  CAS  Google Scholar 

  28. Schumaker, K. S. & Sze, H. J. J. biol. Chem. 262, 3944–3946 (1987).

    CAS  PubMed  Google Scholar 

  29. Irvine, R. F., Letcher, A. J. & Dawson, R. M. C. Biochem. J. 192, 279–283 (1980).

    Article  CAS  Google Scholar 

  30. Helsper, J. P. F. G., DeGroot, P. F. M., Linskens, H. F. & Jackson, J. F. Phytochemistry 25, 2053–2055 (1986).

    Article  Google Scholar 

  31. Elliott, D. & Skinner, J. D. Phytochemistry 25, 39–44 (1986).

    Article  CAS  Google Scholar 

  32. Sandelius, A. S. & Sommarin, M. FEBS Lett. 201, 282–286 (1986).

    Article  CAS  Google Scholar 

  33. Heim, S., Bauleke, A., Wylegalla, C. & Wagner, K. G. Pl. Sci. 49, 159–165 (1987).

    Article  CAS  Google Scholar 

  34. Boss, W. F. & Massel, M. O. Biochem. biophys. Res. Commun. 132, 1018–1023 (1985).

    Article  CAS  Google Scholar 

  35. Heim, S. & Wagner, K. G. Biochem. biophys. Res. Commun. 134, 1175–1181 (1986).

    Article  CAS  Google Scholar 

  36. Morse, M. J., Crain, R. C. & Satter, R. L. Pl. Physiol. 83, 640–644 (1987).

    Article  CAS  Google Scholar 

  37. Morre, D. J., Gripshover, B., Monroe, A. & Morre, J. T. J. biol. Chem. 259, 15364–15368 (1984).

    CAS  PubMed  Google Scholar 

Download references

Author information

Author notes

  1. L. Lehle: To whom correspondence should be addressed.

Authors and Affiliations

  1. Fakultät für Biologic, Universität Regensburg, Universitätsstrasse 31, 8,400, Regensburg, FRG

    C. Ettlinger & L. Lehle

Authors
  1. C. Ettlinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. Lehle
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ettlinger, C., Lehle, L. Auxin induces rapid changes in phosphatidylinositol metabolites. Nature 331, 176–178 (1988). https://doi.org/10.1038/331176a0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/331176a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing