Abstract
CYTOSKELETAL control of cell surface receptor movements1 has been suggested by several authors2,3 and is compatible with the fluid mosaic model of cell membranes4. Evidence for this hypothesis comes mostly from experiments using drugs which alter the activity of cytoskeletal components3,5,6. We report here co-capping of actin and tubulin with immunoglobulins (Ig) in B lymphocytes from mouse spleen. These findings provide structural evidence for cytoskeletal control of receptors.
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GABBIANI, G., CHAPONNIER, C., ZUMBE, A. et al. Actin and tubulin co-cap with surface immunoglobulins in mouse B lymphocytes. Nature 269, 697–698 (1977). https://doi.org/10.1038/269697a0
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DOI: https://doi.org/10.1038/269697a0
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