Abstract
To delineate some of the relationships between membrane composition and the functional states of mammalian cells, we are exploring the possibility of producing controlled modifications in the plasma membrane of cultured cells, using artificially generated lipid vesicles1–3. Although other groups have reported the use of lipid dispersions for producing cellular modifications4–10, the underlying molecular mechanisms by which these effects are produced have not been determined. We present here preliminary findings on the mechanism of interaction of chemically and physically well-defined phospholipid vesicles with cultured mammalian cells.
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PAGANO, R., HUANG, L. & WEY, C. Interaction of phospholipid vesicles with cultured mammalian cells. Nature 252, 166–167 (1974). https://doi.org/10.1038/252166a0
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DOI: https://doi.org/10.1038/252166a0
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