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Determination of Diffusion Coefficients of Haemocyanin at Low Concentration by Intensity Fluctuation Spectroscopy of Scattered Laser Light

Abstract

Electronic analysis of optical signals, known as digital autocorrelation of clipped photon-counting fluctuations, has been used to measure diffusion coefficients of haemocyanin at concentrations ranging from 0.08 to 12.0 mg/ml. At 0.5 mg/ml., with laser power 30 mW, I per cent accuracy is achieved with a measurement time of only 30 s.

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FOORD, R., JAKEMAN, E., OLIVER, C. et al. Determination of Diffusion Coefficients of Haemocyanin at Low Concentration by Intensity Fluctuation Spectroscopy of Scattered Laser Light. Nature 227, 242–245 (1970). https://doi.org/10.1038/227242a0

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