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Absorption of Nicotine in Cigarette and Cigar Smoke through the Oral Mucosa

Abstract

Nicotine in cigar smoke (pH 8.5) is much more readily absorbed through the mucous membranes of the mouth than is nicotine in cigarette smoke (pH 5.3) because there is a higher concentration of unionized nicotine in the relatively alkaline cigar smoke.

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ARMITAGE, A., TURNER, D. Absorption of Nicotine in Cigarette and Cigar Smoke through the Oral Mucosa. Nature 226, 1231–1232 (1970). https://doi.org/10.1038/2261231a0

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