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Identification of Sugars as their Trifluoroacetyl Polyol Derivatives

Abstract

IDENTIFICATION and characterization of mixtures of sugars by gas–liquid chromatography (GLC) have posed considerable difficulty since the advent of the technique1,2. The principal problems have been: (a) the isomerism of the sugars, giving several peaks for each sugar, and (b) the lack of sugar derivatives with sufficient volatility and stability to avoid overlong retention times and degradation during chromatographic separation.

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SHAPIRA, J. Identification of Sugars as their Trifluoroacetyl Polyol Derivatives. Nature 222, 792–793 (1969). https://doi.org/10.1038/222792a0

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