Abstract
SABINE1 demonstrated the antibiotic-like effect of Lactobacillus acidophilus by growing it in a solid medium in holes cut in a plate seeded with a staphylococcus and Escherichia coli as test organisms. He stated that the inhibition observed was not a result of acidity, since there was no difference in the pH of the agar in the cup, in the inhibition zone or in the outer zone. The antibiotic substance was said to be extremely labile and had not yet been isolated.
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References
Sabine, D. B., Nature, 199, 811 (1963).
Ritter, P., Schweiz. Milchztg., 82, (17, Wissenschaft. Beilage No. 35), 273 (1956).
Shillinglaw, C. A., and Levine, M., Food Res., 8, 464 (1943).
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TRAMER, J. Inhibitor Effect of Lactobacillus acidophilus. Nature 211, 204–205 (1966). https://doi.org/10.1038/211204a0
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DOI: https://doi.org/10.1038/211204a0
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